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Methoxetamine, often abbreviated as MXE, is a dissociative drug that is chemically similar to ketamine and phencyclidine (PCP). It was developed in the early 2010s and gained popularity as a recreational drug. MXE is known for its hallucinogenic and dissociative effects, which can alter perception, mood, and cognitive processes. It is typically used for its euphoric and mind-altering properties, but it can also lead to adverse effects such as confusion, agitation, and impaired motor function. Due to its potential for abuse and lack of medical use, MXE is classified as a controlled substance in many countries. CAS No:   1239943-76-0

The chemical and physical properties of Methoxetamine (MXE) in terms of their respective categories:

Chemical Properties:

  • Chemical Structure: Methoxetamine is chemically related to ketamine and has the IUPAC name 2-(3-methoxyphenyl)-2-(ethylamino)cyclohexanone. It features a cyclohexanone core with an ethylamino group and a methoxyphenyl group.
  • Molecular Formula: C15H21NO2
  • Molecular Weight: Approximately 247.34 g/mol
  • Solubility: It is soluble in organic solvents like ethanol and methanol but less soluble in water.

Physical Properties:

  • Appearance: Methoxetamine typically appears as a white crystalline powder. It can also be found in other forms, such as capsules or tablets.
  • Melting Point: The melting point of methoxetamine is not well-documented in public literature, but it is typically solid at room temperature.

These properties play a role in the substance’s use in both recreational and research settings.

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BUY METHOXETAMINE FOR RESEARCHERS AND ENTHUSIASTS

Methoxetamine, often referred to as MXE, is a research chemical known for its dissociative effects. It has attracted the interest of research chemists, medical professionals, and psychonauts alike due to its unique properties. Derived from ketamine, MXE offers both a fascinating chemical structure and potentially wide-ranging applications in neuroscience and medical research.

This post aims to provide a comprehensive overview of Buy Methoxetamine, touching on its history, legality, chemical properties, mechanisms of action, and current standing in research and recreational domains. Whether you are exploring its potential for advancing medical studies or seeking to understand its effects in comparison to other dissociatives, this guide will give you a deeper insight into MXE while emphasizing responsible and informed research practices.

THE STORIES  OF MXE AND ITS USE IN RESEARCH AND   RECREATIONAL PURPOSES 

Methoxetamine first appeared around 2010 as a novel psychoactive substance (NPS). It was primarily marketed as an alternative to ketamine, boasting a longer duration and a purportedly cleaner dissociative experience. Initially developed for research purposes, Methoxetamine quickly gained traction in the recreational drug scene, particularly among individuals interested in altered states of consciousness.

MXE was often discussed in online forums, including Erowid and Reddit, where psychonauts shared dosage guides, experience reports, and reviews of various vendors. Its euphoric and introspective effects led to its widespread appeal, but its status as an NPS also meant a gap in medical literature and regulation at the time. Over the years, governments reacted by introducing laws to control its distribution, further spurring interest in its use for research purposes.

 THE LEGAL  AND REGULATIONS STRUCTURE  SURROUNDING  TO BUY METHOXETAMINE GLOBALLY

To Buy Methoxetamines legally varies significantly across countries, reflecting the challenges of regulating novel psychoactive substances. It is classified as a controlled substance in many nations, including the United States, the United Kingdom, and several EU countries. For instance, the UK placed Methoxetamine under a Temporary Class Drug Order in 2012, later adding it to the list of Class B drugs under the Misuse of Drugs Act.

Despite these restrictions, researchers can still legally acquire  Methoxetamine in some regions by obtaining proper licenses and permits. The keyword “buy Methoxetamine” often populates online marketplaces catering to research professionals, but sourcing from reputable vendors is crucial to ensure purity and compliance with local laws.

 THE CHEMICAL PROPERTIES AND SYNTHESIS OF METHOXETAMINE

Methoxetamine is classified as an arylcyclohexylamine, a group of compounds known for their dissociative anesthetic effects. Its chemical structure 2-(3-methoxyphenyl)-2-(methylamino)cyclohexanone is closely related to ketamine but features a methoxy group on the benzene ring for enhanced potency.

The synthesis of Methoxetamine follows a multi-step process often starting with cyclohexanone and employing various reagents for functional group modifications. While highly detailed, the synthesis is generally confined to qualified chemists with access to the proper facilities for handling chemicals safely and ensuring purity.

Its functionality as dissociative lies in its ability to interact with NMDA receptors and modulate glutamate transmission, making it an intriguing subject for studying brain chemistry and treatment pathways for neurological disorders.

THE MECHANISMS OF ACTION AND POTENTIAL MEDICAL RESEARCH APPLICATIONS IF YOU BUY  METHOXETAMINE

The primary mechanism if you buy Methoxetamine or action involves antagonizing NMDA (N-methyl-D-aspartate) receptors, similar to ketamine. This disruption of excitatory neurotransmitter activity contributes to its distinct dissociative effects, such as altered perception, disrupted sensory input, and a sense of detachment from one’s physical body.

Research into NMDA receptor antagonists suggests potential applications in treating depression, chronic pain, and other neurological conditions. Ketamine, for instance, has emerged as a breakthrough therapy for treatment-resistant depression. While Methoxetamine has not undergone comparable clinical trials, its unique chemical structure raises questions about whether it could exhibit similar, or potentially superior, therapeutic benefits.

TO BUY METHOXETAMINE IN COMPARISON TO OTHER DISSOCIATIVE DRUGS

To Buy Methoxetamine is most often compared to ketamine due to their structural similarities and shared mechanisms of action. However, MXE is typically described as having a longer duration (up to 3-4 hours) and a less sedative profile when compared to ketamine.

MXE is also distinct from PCP (phencyclidine) and DXM (dextromethorphan), both of which are dissociatives known for more erratic effects. Researchers have noted that buying Methoxetamine provides a more controlled and coherent dissociative experience, making it easier to study in laboratory settings.

THE SAFETY CONCERNS AND POTENTIAL SIDE EFFECTS IF YOU  BUY METHOXETAMINE USE

While buying Methoxetamine offers intriguing possibilities for research, safety concerns must remain at the forefront of any study. Reports from the recreational community highlight side effects such as nausea, confusion, motor impairment, and cardiovascular stress. Chronic use may result in dependency, bladder-related issues similar to ketamine-induced cystitis, and potentially cognitive decline.

Notably, the lack of rigorous clinical studies means Methoxetamine’s long-term effects remain poorly understood. Researchers handling MXE should exercise caution, adhere to ethical practices, and advocate for more controlled studies to bridge these knowledge gaps.

CURRENT STUDIES AND FUTURE PROJECTIONS REGARDING HOW TO BUY METHOXETAMINE ARE EVOLVING RAPIDLY

Emerging interest in dissociative anesthetics has positioned Methoxetamine as a potential candidate for further study. Although its recreational history might cast a shadow over its reputation, forward-looking researchers understand the value of exploring novel compounds in the quest for scientific breakthroughs.

With the rise of precision medicine and the growing need for alternative treatments for mental health and neurological conditions, Methoxetamine could see renewed efforts to study its applications in regulated settings. Collaborations between academia, pharmaceutical companies, and regulatory bodies will be crucial in unlocking its potential.

RESPONSIBLE RESEARCH AND USE OF BUY METHOXETAMINE FOR THE FUTURE

BUY METHOXETAMINE occupies a unique niche in the chemical and pharmacological landscape. Its mechanisms of action, versatility, and potential therapeutic applications make it a compound of interest for researchers worldwide.

However, responsible research and use must guide the inquiry into MXE. Researchers are encouraged to source their materials responsibly, engage in transparent and ethical experimentation, and contribute to a growing body of evidence that could transform MXE’s standing in both science and society.

For those exploring the next steps in research to buy Methoxetamine, it’s critical to prioritize safety, legality, and collaboration in unveiling the untapped potential of this fascinating compound.

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A-PVP (alpha-Pyrrolidinovalerophenone), also known as Flakka, is a synthetic stimulant that belongs to the class of compounds called substituted cathinones. These compounds are structurally similar to amphetamines and often have powerful stimulant effects on the central nervous system. A-PVP is chemically related to pyrovalerone, a drug originally developed for the treatment of fatigue, though it is not widely used in clinical practice. As a stimulant, A-PVP can cause effects similar to those of other drugs like cocaine and methamphetamine, such as increased energy, euphoria, and alertness. However, it is also associated with significant risks, including agitation, hallucinations, delirium, and violent behavior. Flakka, which is the street name for A-PVP, gained notoriety due to its association with dangerous behaviors and mental health effects, particularly in certain regions where it was sold as a cheaper alternative to other stimulants. The drug is often found in a white or off-white crystalline form and can be ingested through various methods, including smoking, snorting, or injecting. Due to its potential for abuse and the severe health risks it poses, A-PVP is classified as a controlled substance in many countries, and its use can lead to serious physical and psychological harm. Below is the chemical and physical properties of A-PVP Crystal
Chemical Properties:
  • Chemical Formula: C15H21NO
  • Molecular Weight: Approximately 231.33 g/mol
  • Structure: A-PVP is a ketone analog of prolintane and is structurally related to other synthetic cathinones like MDPV.
  • Functional Groups: Contains a pyrrolidine ring, a phenyl group, and a ketone group.
Physical Properties:
  • Appearance: A-PVP typically appears as a crystalline powder, which can vary in color from white to light brown.
  • Solubility: Soluble in organic solvents like ethanol and methanol but has limited solubility in water.
  • Melting Point: The melting point of A-PVP is not well-documented in public literature, but similar compounds typically have melting points in the range of 100-150°C.
(Note: A-PVP is a controlled substance in many countries, and handling or studying it should be done in compliance with local regulations.)
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Amphetamine powder is a potent stimulant that directly impacts the central nervous system. It is commonly seen as an off-white or pinkish powder, sometimes appearing as small crystalline particles. Amphetamines have both medical and non-medical uses. Below we will examine the chemical and physical properties of Amphetamine.

Chemical Properties:

  • Chemical Formula: C9H13N
  • Molecular Weight: 135.21 g/mol
  • Structure: Amphetamine is a chiral compound, meaning it has two enantiomers: dextroamphetamine and levoamphetamine. The dextro form is more pharmacologically active.
  • Solubility: It is soluble in water and alcohol, which makes it versatile for various formulations.

Physical Properties:

  • Appearance: Amphetamine typically appears as a white, crystalline powder.
  • Melting Point: The melting point of amphetamine is around 91-92°C (196-198°F).
  • Boiling Point: It has a boiling point of approximately 203°C (397°F) at 760 mmHg.
  • Odor: It generally has a faint, characteristic odor.

These properties make amphetamine a widely used substance in both medical and illicit contexts, primarily for its stimulant effects.

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Buphedrone, also known as α-methylamino-butyrophenone (MABP), is a stimulant drug classified within the phenethylamine and cathinone chemical families. It has structural and pharmacological similarities to other synthetic cathinones, which are sometimes colloquially referred to as "bath salts." These compounds often act as central nervous system stimulants, producing effects akin to amphetamines and cocaine. the chemical and physical properties of Buphedone are as follows:

Chemical Properties:

  • Chemical Formula: C11H15NO
  • Molecular Weight: 177.24 g/mol
  • IUPAC Name: 2-(methylamino)-1-phenylbutan-1-one
  • Structure: It contains a phenyl ring bonded to a butanone chain with a methylamino group.

Physical Properties:

  • Appearance: Typically, buphedrone is found as a white crystalline powder.
  • Solubility: It is soluble in water and organic solvents like ethanol.
  • Melting Point: The exact melting point can vary, but it is generally in the range typical for cathinones.

Buphedrone is known for its stimulant effects, similar to other cathinones, and is often used recreationally. However, it is important to note that the use of buphedrone can be associated with health risks and legal issues in many jurisdictions.

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For those thinking to buy Fentanyl powder is an illicit form of fentanyl, a synthetic opioid that is far stronger than many other opioids, including morphine and heroin. While fentanyl is medically prescribed for severe pain, such as post-surgery recovery or for patients with chronic pain, it is highly dangerous when abused or improperly used. In its powdered form, fentanyl is often mixed with other substances, increasing the risk of overdose, as it can be difficult to measure the correct dose. Fentanyl works by binding to the body's opioid receptors, which control pain and emotions. It can induce powerful effects such as pain relief, euphoria, and respiratory depression. The risk of overdose is especially high with fentanyl because its potency can easily lead to fatal respiratory depression if someone unknowingly consumes a dose too large for their tolerance. Even a tiny amount of fentanyl can be lethal, which is why its misuse is particularly hazardous. Fentanyl is also associated with a rise in overdose deaths, especially when it is mixed with other illegal drugs, often without the user’s knowledge. The compound with the chemical formula C₂₂H₂₈N₂O is likely a complex organic compound, though it is not a widely recognized or well-documented substance in common chemical databases. Based on the given details, here's an attempt to describe its chemical and physical properties:

Chemical Properties:

  • Molecular Formula: C₂₂H₂₈N₂O suggests an organic compound with nitrogen (N), oxygen (O), and carbon (C) atoms. It could be a type of amine or amide, or a related compound involving nitrogen and oxygen functionality.
  • Functional Groups: The presence of nitrogen and oxygen hints that this compound could have functional groups such as amines (–NH₂), amides (–CONH₂), or ethers (–O–), but the exact functional groups would depend on the full structure.
  • Reactivity: The compound may react under conditions typical for organic molecules containing nitrogen and oxygen, such as acid-base reactions, nucleophilic substitution, or ester hydrolysis (if an ester group is present). It may also undergo combustion, polymerization, or oxidation under certain conditions.

Physical Properties:

  • Solubility: As stated, this compound is slightly soluble in water. The slight solubility is a characteristic common to many large organic compounds. The solubility could be influenced by the structure and intermolecular forces (e.g., hydrogen bonding, Van der Waals forces) in the compound.
  • Form: The compound is described as solid and can exist in either a crystal or crystalline powder form. This suggests it has a defined and organized molecular structure capable of forming crystals.
  • Boiling Point: The boiling point is not well-established. This could be due to a lack of detailed studies or because the compound may decompose before reaching a boiling point. Large organic compounds like this often have high boiling points, but specific data is required to be sure.
  • Density: The density is also not well-established, but it can be speculated that its density would depend on its molecular weight and the packing arrangement of its solid form. Organic solids with similar molecular weights can have densities ranging from 1.0 to 1.5 g/cm³.
Given that fentanyl citrate (a related compound) is more soluble in water, this compound may have similar molecular characteristics but with a different solubility profile due to the variations in their structures.
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Ketamine injection is primarily used as a dissociative anesthetic to induce loss of consciousness before and during surgery or medical procedures. It works by disrupting the transmission of pain signals in the brain while maintaining basic life functions, which makes it especially useful in certain medical contexts, including emergency medicine and for patients with unstable vital signs. It is typically administered by a healthcare provider through intravenous (IV) or intramuscular (IM) injection. Below are the chemical and physical properties of  Ketamine injection

Chemical Properties:

  1. Chemical Formula: C13H16ClNO
  2. Molecular Weight: Approximately 237.7 g/mol
  3. Structure: Ketamine is a chiral compound, typically used as a racemic mixture of its two enantiomers.
  4. Solubility: Ketamine is soluble in water and alcohol, which is important for its formulation as an injectable solution.

Physical Properties:

  1. Appearance: Ketamine Injection is usually a clear, colorless to slightly yellow solution.
  2. pH: The pH of the injectable solution is typically between 3.5 and 5.5.
  3. Formulation: It is available in various concentrations, commonly 10 mg/mL, 50 mg/mL, and 100 mg/mL.

These properties are crucial for its pharmacokinetics and pharmacodynamics, influencing how the drug is absorbed, distributed, metabolized, and excreted in the body.

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MDPV, or Methylenedioxypyrovalerone, is a synthetic stimulant of the cathinone class. It was first developed in the 1960s and gained popularity as a recreational drug in the 2000s. MDPV is known for its potent stimulant effects, which can include increased alertness, euphoria, and heightened energy levels. However, it also has a high potential for abuse and can lead to severe side effects such as anxiety, paranoia, and hallucinations. Due to its potential for harm, MDPV is classified as a controlled substance in many countries.

Here are the  chemical and physical properties of MDPV:

Chemical Properties:

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  • Molecular Weight: 275.35 g/mol
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  • Structure: MDPV contains a methylenedioxyphenyl group attached to a pyrrolidinyl group via a pentanone chain.

Physical Properties:

  • Appearance: MDPV typically appears as a white or off-white powder.
  • Melting Point: Approximately 170-175°C
  • Solubility: It is soluble in water and organic solvents like ethanol and methanol.

MDPV is known for its stimulant effects, similar to those of cocaine and amphetamines, and has been associated with various health risks and legal issues. Always handle with caution and awareness of its legal status in your area.

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Methylone, also known as 3,4-methylenedioxy-N-methylcathinone, is a synthetic stimulant and entactogen of the amphetamine, phenethylamine, and cathinone classes. It is chemically similar to MDMA (ecstasy) and is often used recreationally for its euphoric and empathogenic effects. Methylone was initially developed as an antidepressant but is now more commonly encountered as a recreational drug. It is important to note that the legal status of methylone varies by country, and it may be classified as a controlled substance in many places due to its potential for abuse and health risks.

Here are the  chemical and physical properties to consider before you buy Methylone :

Chemical Properties:

  • Chemical Formula: C11H13NO3
  • Molecular Weight: 207.23 g/mol
  • Structure: Methylone is a beta-keto analogue of MDMA, meaning it has a ketone group at the beta position of the side chain.
  • IUPAC Name: 1-(1,3-benzodioxol-5-yl)-2-(methylamino)propan-1-one

Physical Properties:

  • Appearance: Methylone typically appears as a white or off-white crystalline powder.
  • Solubility: It is soluble in water and organic solvents like ethanol.
  • Melting Point: The melting point of methylone is around 147-148°C.

Methylone is often used recreationally and is known for its psychoactive effects, which can include euphoria, increased energy, and altered sensory perception. However, it is important to note that the use of methylone can have significant legal and health implications.

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 U-47700 Fentanyl Analogues

U-47700 is a synthetic opioid that, while not structurally related to fentanyl, is frequently discussed alongside fentanyl analogs because of its similar potency and associated risks. Below are key points about U-47700 and fentanyl analogs:

U-47700

  • Structure: U-47700 belongs to the class of synthetic opioids but does not share the structural backbone of fentanyl. Instead, it was initially developed as a potential painkiller.
  • Potency: It is highly potent and has effects comparable to other powerful opioids, including euphoria, pain relief, and respiratory depression.
  • Risks: U-47700 has been associated with numerous cases of intoxication and fatalities, largely due to its small therapeutic window and high risk of overdose.
  • Legal Status: Due to its abuse potential and associated risks, U-47700 has been classified as a Schedule I controlled substance in several countries, meaning it has no accepted medical use.

Fentanyl Analogues

  • Definition: Fentanyl analogs are chemically modified versions of fentanyl, a prescription opioid used for severe pain management.
  • Potency: These analogs are often even more potent than fentanyl itself, with some being hundreds of times stronger than morphine.
  • Risks: Due to their potency, even a small amount can cause respiratory failure and death, making them a significant contributor to the opioid overdose crisis.
  • Illicit Use: Fentanyl analogs are frequently manufactured and distributed illegally, often mixed with other drugs or pressed into counterfeit pills, increasing the risk of unintentional overdoses.

Commonalities Between U-47700 and Fentanyl Analogues

  • Both have been involved in opioid-related intoxications and fatalities.
  • Both are characterized by their high potency and narrow margin of safety.
  • Both are associated with the illegal drug market and are significant contributors to the opioid epidemic.
While U-47700 and fentanyl analogs are not structurally similar, their comparable potency and associated dangers place them within the broader discussion of synthetic opioids

Chemical Properties of U-47700

  • Molecular Formula: C₁₆H₂₂Cl₂N₂O
  • Molecular Weight: 329.3 g/mol
  • Chemical Structure:
    • Core Structure: Trans-3,4-dichloro-N-(2-(dimethylamino)cyclohexyl)-N-methylbenzamide.
    • Includes dichloro-substituents on the benzamide ring and a dimethylamino group.
  • Pharmacology: Acts as a synthetic opioid with analgesic effects.

Fentanyl Analogues

  • Molecular Formula: Varies depending on the analogue, but is based on the fentanyl core structure (C₂₂H₂₈N₂O).
  • Chemical Modifications: Slight structural changes to fentanyl's backbone (e.g., substitutions on the piperidine ring or changes in the phenethyl group).
  • Molecular Weight: Varies with the analog but typically in the range of 300-400 g/mol.
  • Pharmacology: Extremely potent synthetic opioids, often 50–100 times stronger than morphine.

Physical Properties of U-47700

  • Appearance: Often found as a white or light pink powder (hence the street name "Pinky").
  • Melting Point: Approximately 218–222°C (based on analogous structures).
  • Solubility: Soluble in organic solvents; limited solubility in water.

Fentanyl Analogues

  • Appearance: Typically white to off-white powders, liquids, or transdermal patches, depending on the preparation.
  • Melting Point: Varies depending on the specific analogue; typically ranges between 86°C and 106°C for fentanyl base.
  • Solubility: High solubility in organic solvents; also soluble in water and lipids, contributing to high potency and rapid absorption.
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